Quartz Wafer Nanoimprint Biochip with Sub-10nm Nanochannels for DNA Sequencing

Product Description

Nanoimprint Engineered Chip

 

· Product Description

ZEGOTA's Gene Sequencing Chips are state-of-the-art microfluidic and nanopore-based platforms engineered for next-generation (NGS) and third-generation (TGS) genetic analysis. Specializing in high-throughput Nanoimprint Lithography (NIL) , we break the cost-and-scaling barriers of traditional photolithography, delivering mass-producible sub-20nm feature sizes with absolute structural fidelity.
Leveraging semiconductor-grade fabrication and advanced surface functionalization, ZEGOTA provides a fully integrated OEM/ODM pipeline-spanning from structural prototyping and pilot testing to automated, high-volume foundry production. Our NIL-driven platforms ensure world-class surface uniformity, extreme chemical resistance, and precise micro/nano-channel fidelity required for single-molecule accuracy and massive parallel processing.
 

· Core Technical Advantages & Global Benchmark

Next-Gen Nanoimprint (NIL) Mastery: Our proprietary nanoimprint replication technology achieves critical feature sizes $\le 20\text{ nm}$ (with an active R&D capability down to $10\text{ nm}$ for ultra-dense nanopore arrays). This matches and exceeds the specifications of international tier-1 sequencing flow cells, ensuring maximum cluster density and optical/electrical signal SNR.

Hybrid Multi-Process Integration: We seamlessly combine large-scale photolithography (for microfluidic supply channels) with ultra-precise nanoimprint lithography (for nanoscale capturing zones) under one roof. This allows for complex, multi-tier hybrid structures (e.g., micro-flows integrated with nano-gaps) that single-technology vendors cannot manufacture.

Flawless Surface Chemistry: We offer top-tier molecular surface modification (CVD/liquid phase), including uniform PEGylation, aminosilane alignment, and streptavidin immobilization. Our surface uniformity variation is kept within $\pm 2\%$, minimizing non-specific binding and optimizing DNA/RNA polymerase anchoring.

Semiconductor-Grade Cleanrooms: Produced in ultra-strict Class 10/100 localized clean zones inside our Class 10k/100k GMP environments, guaranteeing zero particulate defect rates and strict fluidic consistency.
 

· Target Applications

Our NIL-engineered sequencing chips and specialized foundry services power critical global life-science sectors:
Next-Generation Sequencing (NGS): Ultra-high-density patterned flow cells optimized for massive bridge amplification clusters.
Third-Generation Sequencing (TGS): Nanopore arrays and Single-Molecule Real-Time (SMRT) sequencing zero-mode waveguide (ZMW) arrays.
Molecular Diagnostics & POCT: Precision micro-nano hybrid fluidic chips for fast sample processing and digital PCR (dPCR) partitioning.
Organ-on-a-Chip & Bio-MEMS: Biomimetic nanostructure channels replicating extracellular matrices for advanced toxicity screening.
 

· Product Parameters (Benchmarked to Tier-1 Standards)

Capability Item	Description / International Standard Specs
Primary Technology	Advanced Nanoimprint Lithography (NIL), Hybrid Photolithography, CVD Surface Engineering
Chip Architectures	Silicon-based, Glass-based, Quartz-based, and Polymer (COC/COP/PMMA) chips
NIL Resolution (Feature Size)	≤20nm (Nanopore arrays, nano-channels, nano-gaps, ZMW arrays)
CD Uniformity (Wafer-level)	Within ±3% across standard 6-inch / 8-inch substrates
Surface Modification	Hydrophilic/Hydrophobic tuning, PEGylation, Silanization, Biotin-Streptavidin coating
Cleanroom Standard	Class 100 localized, Class 10k/100k facility, GMP Class 10,000
Quality Management	ISO 13485:2016 (Medical Devices Quality), FDA Registered, CE Compliant
Foundry Service Model	Concept R&D → NIL Mold Making →  Prototype → Pilot →  High-Volume OEM

· Brief Introduction

  Zhejiang ZEGOTA Precision Technology Co., Ltd. is a premier, technology-driven pioneer specializing in high-precision semiconductor-grade micro and nanofabrication. Armed with industry-leading Nanoimprint Lithography (NIL) technology and a world-class multidisciplinary R&D team, ZEGOTA provides customized foundry services that meet the rigorous demands of precision medicine and genomic healthcare.
  By unifying structural design, mold nano-fabrication, surface functionalization, and high-volume replication under one roof , we do not just supply hardware-we accelerate the commercialization of next-generation biotechnology worldwide.